What is pre-fibrotic myelofibrosis and how should it be managed in 2018?

Artificial Intelligence: What It Is, and What It Should Be

What Artificial Intelligence (AI) is at the current time is not what it should be. The mainstream works in the field are on domain-specific problems and solutions. Instead, AI should focus on general-purpose systems that are adaptive to its environment, and can work with insufficient knowledge and resources. AI in this sense is unified with Cognitive Science at a general level, with the latter ...

How should chylothorax be managed?

The management and complications of chylothorax occurring beyond the neonatal period were reviewed retrospectively. Records from 15 patients treated between 1976 and 1986 were analysed; a combination of thoracocentesis, chest drain insertion, and dietary modification were successful in abolishing chyle leakage in 10 cases. One child died from complications of cardiac surgery rather than from th...

Tigecycline: what is it, and where should it be used?

Tigecycline is the first glycylcycline to be launched and is one of the very few new antimicrobials with activity against Gram-negative bacteria. It evades acquired efflux and target-mediated resistance to classical tetracyclines, but not chromosomal efflux in Proteeae and Pseudomonas. Cmax+ is low, but tissue penetration is excellent and the compound has shown equivalence to imipenem/cilastati...

Posttonsillectomy hemorrhage: what is it and what should be recorded?

OBJECTIVES To report on our incidence of posttonsillectomy hemorrhage and to define what constituted posttonsillectomy bleeding. DESIGN Retrospective study. SETTING Tertiary care children's hospital and a local satellite facility. PATIENTS A series of 1438 consecutive patients who had undergone either tonsillectomy or adenotonsillectomy between January 1, 1999, and December 31, 1999. IN...

What is osteopenia, and what should be done about it?